Angiogenesis
Apoptosis
Autophagy
Cell Cycle
Cytoskeletal Signaling
DNA Damage
Endocrinology&Hormones
Epigenetics
ER stress & UPR
GPCR & G Protein
Immunology&Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
Metabolism
Microbiology
Natural products
Neuronal Signaling
NF-κB
PI3K/Akt/mTOR
Proteases
Protein Tyrosine Kinase
Stem Cells & Wnt
TGF-beta/Smad
Transmembrane Transporters
Ubiquitin
Others
Screening library
Peptide
Enzymes and proteins
Sphingolipids
Amino acid
Carbohydrates
Dyeing and dyes
Nucleotides
Vitamins
Analytical Standards
Drug impurity
Derivative analytical reagent
Chromatographic solvent
Analysis materials
Chiral compounds
Amino acid derivatives
Catalysts and Ligands
Benzene ring compounds
Indole compounds
Pyridine compounds
Other heterocyclic compounds
Other synthetic blocks
Inorganic salt
Proteins and Peptides
Analysis and preparation
Chiral analysis and preparation
Customized synthesis
>
ARS-853
TS3401-1MG
In-stock
260
- +
TS3401-5MG
940
Product Name
Synonym
1-[3-[4-[2-[4-chloro-2-hydroxy-5-(1-methylcyclopropyl)anilino]acetyl]piperazin-1-yl]azetidin-1-yl]prop-2-en-1-one
CAS No.
1629268-00-3
Purity
≥98.5%
Formula
C22H29ClN4O3
Molecular Weight
432.94
Description
ARS-853 is a selective, covalent KRAS(G12C) inhibitor that inhibits mutant KRAS-driven signaling by binding to the GDP-bound oncoprotein and preventing activation.
