Product Name

Peficitinib (ASP015K, JNJ-54781532)

General description

Peficitinib (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor.

Synonym

4-[[(1R,3S)-5-hydroxy-2-adamantyl]amino]-1H-pyrrolo[2,3-b]pyridine-5-carboxamide

Purity

≥98.5%(HPLC)

CAS Number

944118-01-8

Formula

C¹⁸H²²N⁴O²

Molecular Weight

326.39

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Solid

Solubility(25°C)

DMSO

≥50mg/ml

Ethanol

Insoluble

Water

Very slightly soluble

l  Biological Information

Biochem/Physiol  Actions

Peficitinib has been used in trials studying the treatment and basic science of Psoriasis, Pharmacodynamics, Drug Interactions, Colitis, Ulcerative, and RHEUMATOID ARTHRITIS, among others.

Application

1.Enzyme Inhibitors

2.Immunosuppressive Agents

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov