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PF-431396

Product #: TS3167
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Details

l  General Information

Product Name

PF-431396

General description

PF-431396 is a dual PYK2/FAK inhibitor with IC50 of 11 nM and 2 nM, respectively. 

Synonym

N-methyl-N-[2-[[[2-[(2-oxo-1,3-dihydroindol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]methyl]phenyl]methanesulfonamide

Purity

≥98.5%(HPLC)

CAS Number

717906-29-1

Formula

C22H21F3N6O3S

Molecular Weight

506.5

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Off-White to Blue-Gray Solid

Solubility(25°C)

DMSO

≥50mg/mL

Ethanol

Insoluble

Water

Very slightly soluble

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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