Product Name

Niraparib (MK-4827) tosylate

General description

Niraparib (MK-4827) tosylate is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM.

Synonym

4-methylbenzenesulfonic acid; 2-[4-[(3S)-piperidin-3-yl]phenyl]indazole-7-carboxamide

Purity

≥98.5%(HPLC)

CAS Number

1038915-73-9

Formula

C²⁶H²⁸N⁴O⁴S

Molecular Weight

492.59

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Solid

Solubility(25°C)

DMSO

≥50mg/ml

Ethanol

Insoluble

Water

Very slightly soluble

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov