l General Information |
Product Name | Darolutamide (ODM-201) |
General description | Darolutamide (ODM-201) is a novel androgen receptor (AR) antagonist that blocks AR nuclear translocation with Ki of 11 nM. |
Synonym | N-[(2S)-1-[3-(3-chloro-4-cyanophenyl)pyrazol-1-yl]propan-2-yl]-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide |
Purity | ≥98.5%(HPLC) | CAS Number | 1297538-32-9 |
Formula | C19H19ClN6O2 | Molecular Weight | 398.85 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25°C) | DMSO | ≥50mg/mL |
Ethanol | ≥25mg/mL |
Water | Very slightly soluble |
l Biological Information |
Biochem/Physiol
Actions | ODM-201 has been used in trials studying the treatment of Prostate Cancer, Pharmacokinetics, Drug Interaction, Castration-Resistant, and Breast cancer female, among others. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
