l General Information |
Product Name | GDC-0623 |
General description | GDC-0623 is a potent and ATP-uncompetitive MEK1 inhibitor with Ki of 0.13 nM. |
Synonym | G-868; 5-(2-fluoro-4-iodoanilino)-N-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide |
Purity | ≥97.0%(HPLC) | CAS Number | 1168091-68-6 |
Formula | C16H14FIN4O3 | Molecular Weight | 456.21 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25°C) | DMSO | ≥50mg/ml |
Ethanol | ~5mg/ml |
Water | Very slightly soluble |
l Biological Information |
Biochem/Physiol
Actions | GDC-0623 has been used in trials studying the treatment of Solid Cancers. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
