Product Name

XL413 (BMS-863233)

General description

XL413 (BMS-863233) is a potent and selective cell division cycle 7 homolog (CDC7) kinase inhibitor with IC50 of 3.4 nM, showing 63-, 12- and 35-fold selectivity over CK2, Pim-1 and pMCM2, respectively.

Synonym

8-chloro-2-[(2~{S})-pyrrolidin-2-yl]-3~{H}-[1]benzofuro[3,2-d]pyrimidin-4-one; hydrochloride 

Purity

≥98.5%(HPLC)

CAS Number

1169562-71-3

Formula

C¹⁴H¹³Cl²N³O²

Molecular Weight

326.18

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to Beige Solid

Solubility(25°C)

DMSO

Very slightly soluble

Ethanol

Insoluble

Water

≥35mg/ml

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov