l  General Information  | 
Product Name  | WZ4003  | 
General description  | WZ4003 is a highly specific NUAK kinase inhibitor with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2 in cell-base assays, respectively, without significant inhibition on 139 other kinases.  | 
Synonym  | N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]propanamide  | 
Purity  | ≥98.0%(HPLC)  | CAS Number  | 1214265-58-3  | 
Formula  | C25H29ClN6O3  | Molecular Weight  | 496.99  | 
Suitability  | BioReagent, suitable for cell culture, etc.  | 
l  Physical and Chemical Information  | 
Appearance  | White to Beige Solid  | 
Solubility(25°C)  | DMSO  | ~5mg/mL  | 
Ethanol  | Insoluble  | 
Water  | Very slightly soluble  | 
l  Storage  | 
Storage temp.  | -20°C  | 
l  Precautions and Disclaimer  | 
This product is for R&D use only, not for drug, household, or other uses.  | 
l  References  | 
1.    http://www.drugbank.ca 2.    https://ncit.nci.nih.gov 3.    https://www.ncbi.nlm.nih.gov  |