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Home > Products > Small molecule > TGF-beta/Smad > Bisindolylmaleimide IX (Ro 31-8220 Mesylate)

Bisindolylmaleimide IX (Ro 31-8220 Mesylate)

Product #: TS2957
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Details

l  General Information

Product Name

Bisindolylmaleimide IX Mesylate

General description

Bisindolylmaleimide IX Mesylate is a pan-PKC inhibitor with IC50 of 5 nM, 24 nM, 14 nM, 27 nM, and 24 nM for PKC-α, PKC-βI, PKC-βII, PKC-γ, and PKC-ε, respectively, and also shows potent inhibition against MAPKAP-K1b, MSK1, GSK3β and S6K1.

Synonym

Ro 31-8220 Mesylate

Purity

≥98.5%(HPLC)

CAS Number

138489-18-6

Formula

C26H27N5O5S2

Molecular Weight

553.65

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Red Solid

Solubility(25°C)

DMSO

≥50mg/ml

Ethanol

Insoluble

Water

Very slightly soluble

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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