l  General Information  | 
Product Name  | RKI-1447  | 
General description  | RKI-1447 is a potent inhibitor of ROCK1 and ROCK2, with IC50 of 14.5 nM and 6.2 nM, respectively, has anti-invasive and antitumor activities.  | 
Synonym  | 1-[(3-hydroxyphenyl)methyl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)urea    | 
Purity  | ≥98.0%(HPLC)  | CAS Number  | 1342278-01-6  | 
Formula  | C16H14N4O2S  | Molecular Weight  | 326.37  | 
Suitability  | BioReagent, suitable for cell culture, etc.  | 
l  Physical and Chemical Information  | 
Appearance  | Solid  | 
Solubility(25°C)  | DMSO  | ≥50mg/ml  | 
Ethanol  | Insoluble  | 
Water  | Very slightly soluble  | 
l  Storage  | 
Storage temp.  | -20°C  | 
l  Precautions and Disclaimer  | 
This product is for R&D use only, not for drug, household, or other uses.  | 
l  References  | 
1.    http://www.drugbank.ca 2.    https://ncit.nci.nih.gov 3.    https://www.ncbi.nlm.nih.gov  |