l General Information |
Product Name | BAF312 |
General description | BAF312 is a next-generation S1P receptor modulator, selective for S1P1 and S1P5 receptors with EC50 of 0.39 nM and 0.98 nM, exhibits >1000-fold selectivity over S1P2, S1P3 and S1P4 receptors. Phase 3. |
Synonym | Siponimod |
Purity | ≥98.5%(HPLC) | CAS Number | 1230487-00-9 |
Formula | C29H35F3N2O3 | Molecular Weight | 516.6 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25°C) | DMSO | ≥50mg/ml |
Ethanol | ≥35mg/ml |
Water | Very slightly soluble |
l Biological Information |
Biochem/Physiol
Actions | Siponimod has been used in trials studying the treatment of Polymyositis, Dermatomyositis, Renal Impairment, Hepatic Impairment, and Autoimmune Diseases, among others. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
