l General Information |
Product Name | IPA-3 |
General description | IPA-3 is a selective non-ATP competitive Pak1 inhibitor with IC50 of 2.5 μM in a cell-free assay, no inhibition to group II PAKs (PAKs 4-6). |
Synonym | 1-[(2-hydroxynaphthalen-1-yl)disulfanyl]naphthalen-2-ol |
Purity | ≥96.0%(HPLC) | CAS Number | 42521-82-4 |
Formula | C20H14O2S2 | Molecular Weight | 350.45 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Yellow Solid |
Solubility(25°C) | DMSO | ≥50mg/ml |
Ethanol | ~5mg/ml |
Water | Very slightly soluble |
l Biological Information |
Biochem/Physiol
Actions | IPA-3 is an organic disulfide obtained by oxidative dimerisation of 1-sulfanylnaphthalen-2-ol. It has a role as an EC 2.7.11.1 (non-specific serine/threonine protein
kinase) inhibitor. It is an organic disulfide and a member of naphthols. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
