l  General Information  | 
Product Name  | RN486  | 
General description  | RN486 is a potent and selective BTK inhibitor with IC50 of 4 nM.      | 
Synonym  | 6-cyclopropyl-8-fluoro-2-[2-(hydroxymethyl)-3-[1-methyl-5-[[5-(4-methylpiperazin-1-yl)pyridin-2-yl]amino]-6-oxopyridin-3-yl]phenyl]isoquinolin-1-one    | 
Purity  | ≥98.5%(HPLC)  | CAS Number  | 1242156-23-5  | 
Formula  | C35H35FN6O3  | Molecular Weight  | 606.69  | 
Suitability  | BioReagent, suitable for cell culture, etc.  | 
l  Physical and Chemical Information  | 
Appearance  | Solid  | 
Solubility(25°C)  | DMSO  | ≥50mg/ml  | 
Ethanol  | Insoluble  | 
Water  | Very slightly soluble  | 
l  Storage  | 
Storage temp.  | -20°C  | 
l  Precautions and Disclaimer  | 
This product is for R&D use only, not for drug, household, or other uses.  | 
l  References  | 
1.    http://www.drugbank.ca 2.    https://ncit.nci.nih.gov 3.    https://www.ncbi.nlm.nih.gov  |