l General Information |
Product Name | Embelin |
General description | Embelin, a quinone isolated from the Japanese Ardisia herb, is an inhibitor of X-ed inhibitor of apoptosis (XIAP) with IC50 of 4.1 μM in a cell-free assay. |
Synonym | Embelic Acid; NSC 91874; 2,5-dihydroxy-3-undecylcyclohexa-2,5-diene-1,4-dione |
Purity | ≥98.5%(HPLC) | CAS Number | 550-24-3 |
Formula | C17H26O4 | Molecular Weight | 294.39 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25°C) | DMSO | ≥45mg/ml |
Ethanol | ≥5mg/ml |
Water | Very slightly soluble |
l Biological Information |
Biochem/Physiol
Actions | Embelin is a member of the class of dihydroxy-1,4-benzoquinones that is 2,5-dihydroxy-1,4-benzoquinone which is substituted by an undecyl group at position 3. Isolated from Lysimachia punctata and Embelia ribes, it exhibits antimicrobial, antineoplastic and inhibitory activity towards hepatitis C protease. It has a role as a hepatitis C protease inhibitor, an antimicrobial agent, an antineoplastic agent and a plant metabolite. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
