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Home > Products > Small molecule > PI3K/Akt/mTOR > VS-5584 (SB2343)

VS-5584 (SB2343)

Product #: TS2880
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Details

l  General Information

Product Name

VS-5584

General description

VS-5584 is a potent and selective dual PI3K/mTOR inhibitor for mTOR, PI3Kα/β/δ/γ with IC50 of 3.4 nM and 2.6-21 nM, respectively.

Synonym

SB2343; 5-(8-methyl-2-morpholin-4-yl-9-propan-2-ylpurin-6-yl)pyrimidin-2-amine 

Purity

≥98.5%(HPLC)

CAS Number

1246560-33-7

Formula

C17H22N8O

Molecular Weight

354.41

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Solid

Solubility(25°C)

DMSO

≥50mg/ml

Ethanol

Slightly soluble

Water

Very slightly soluble

l  Biological Information

Biochem/Physiol  Actions

VS-5584 has been used in trials studying the treatment of Lymphoma, Metastatic Cancer, and Non Hematologic Cancers.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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