l General Information |
Product Name | Fluorometholone |
General description | Fluorometholone is a synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. It is usually used as eye drops in the treatment of allergic and inflammatory conditions of the eye. |
Synonym | Oxylone |
Purity | ≥98.0%(HPLC) | CAS Number | 426-13-1 |
Formula | C22H29FO4 | Molecular Weight | 376.46 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White to Off White Solid |
Solubility(25°C) | DMSO | ≥50mg/ml |
Ethanol | ~5mg/ml |
Water | Very slightly soluble |
l Biological Information |
Biochem/Physiol
Actions | Fluorometholone is a synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. Fluorometholone exerts its effects by interacting with cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor mediated gene . The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
