l General Information |
Product Name | Butoconazole |
General description | Butoconazole is an imidazole antifungal used in gynecology. |
Synonym | Butoconazolum; Butoconazol; Butaconazole; Femstat; 1-[4-(4-chlorophenyl)-2-(2,6-dichlorophenyl)sulfanylbutyl]imidazole |
Purity | ≥98.0%(HPLC) | CAS Number | 64872-76-0 |
Formula | C19H17Cl3N2S | Molecular Weight | 411.78 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25°C) | DMSO | ≥50mg/ml |
l Biological Information |
Biochem/Physiol
Actions | Butoconazole is a synthetic imidazole derivative with fungistatic properties. Butoconazole interferes with steroid biosynthesis by inhibiting the conversion of lanosterol to ergosterol, thereby changing the fungal cell membrane lipid composition. This alters cell permeability and leads to growth inhibition. Butaconazole nitrate is active against many dermatophytes and yeasts. It also contains antibacterial effects against some gram-positive organisms. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
