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Regadenoson

Product #: TS2570
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Details

l  General Information

Product Name

Regadenoson

General description

Regadenoson is a selective A2A adenosine receptor agonist with coronary vasodilating activity.

Synonym

CVT-3146, Lexiscan

Purity

≥99.0%(HPLC)

CAS Number

313348-27-5

Formula

C15H18N8O5

Molecular Weight

390.35402

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to beige Solid

Solubility(25°C)

DMSO

≥50mg/ml

Ethanol

Slightly soluble

Water

Very slightly soluble

l  Biological Information

Biochem/Physiol  Actions

Regadenoson is an adenosine derivative and selective A2A adenosine receptor agonist with coronary vasodilating activity. Upon administration, regadenoson selectively binds to and activates the A2A adenosine receptor, which induces coronary vasodilation. This leads to an increase in coronary blood flow and enhances myocardial perfusion. Compared to adenosine, regadenoson has a longer half-life and shows higher selectivity towards the A2A adenosine receptor. This agent is a very weak agonist for the A1 adenosine receptor and has negligible affinity for the A2B and A3 adenosine receptors.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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