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Nitisinone

Product #: TS2545
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l  General Information

Product Name

Nitisinone

General description

Nitisinone is a synthetic reversible inhibitor of 4-hydroxyphenylpyruvate dioxygenase used in the treatment of hereditary tyrosinemia type 1.

Synonym

Orfadin; Nitisone; NTBC; 2-(2-Nitro-4-(Trifluoromethyl)Benzoyl)Cyclohexane-1,3-Dione

Purity

≥98.0%(HPLC)

CAS Number

104206-65-7

Formula

C14H10F3NO5

Molecular Weight

329.23

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to brown Solid

Solubility(25°C)

DMSO

≥50mg/ml

Ethanol

Insoluble

Water

Very slightly soluble

l  Biological Information

Biochem/Physiol  Actions

Nitisinone is a Hydroxyphenyl-Pyruvate Dioxygenase Inhibitor. The mechanism of action of nitisinone is as a Hydroxyphenylpyruvate Dioxygenase Inhibitor.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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