l General Information |
Product Name | Nitisinone |
General description | Nitisinone is a synthetic reversible inhibitor of 4-hydroxyphenylpyruvate dioxygenase used in the treatment of hereditary tyrosinemia type 1. |
Synonym | Orfadin; Nitisone; NTBC; 2-(2-Nitro-4-(Trifluoromethyl)Benzoyl)Cyclohexane-1,3-Dione |
Purity | ≥98.0%(HPLC) | CAS Number | 104206-65-7 |
Formula | C14H10F3NO5 | Molecular Weight | 329.23 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White to brown Solid |
Solubility(25°C) | DMSO | ≥50mg/ml |
Ethanol | Insoluble |
Water | Very slightly soluble |
l Biological Information |
Biochem/Physiol
Actions | Nitisinone is a Hydroxyphenyl-Pyruvate Dioxygenase Inhibitor. The mechanism of action of nitisinone is as a Hydroxyphenylpyruvate Dioxygenase Inhibitor. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |