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NU2058

Product #: TS2537
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Details

l  General Information

Product Name

NU2058

General description

NU2058 is an inhibitor of CDK2 with IC50 value of 17 μM in an isolated enzyme assay. It also potentiates melphalan (DMF 2.3), and monohydroxymelphalan (1.7), but not temozolomide or ionising radiation.

Synonym

O(6)-Cyclohexylmethylguanine; 6-(cyclohexylmethoxy)-7H-purin-2-amine

Purity

≥98.0%(HPLC)

CAS Number

161058-83-9

Formula

C12H17N5O

Molecular Weight

247.30

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to off-white Solid

Solubility(25°C)

DMSO

≥35mg/ml

Ethanol

≥35mg/ml

Water

Very slightly soluble

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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