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Nimustine Hydrochloride

Product #: TS2518
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l  General Information

Product Name

Nimustine Hydrochloride

General description

Nimustine Hydrochloride is the hydrochloride salt of nimustine, a nitrosourea with antineoplastic activity that alkylates and crosss DNA, thereby causing DNA fragmentation, inhibition of protein synthesis, and cell death.

Synonym

Nidran hydrochloride; 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-1-(2-chloroethyl)-1-nitrosourea; hydrochloride 

Purity

≥98.0%(HPLC)

CAS Number

55661-38-6

Formula

C9H14Cl2N6O2

Molecular Weight

309.15

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Solid

Solubility(25°C)

DMSO

≥50mg/ml

l  Biological Information

Biochem/Physiol  Actions

Nimustine Hydrochloride is the hydrochloride salt of nimustine, a nitrosourea with antineoplastic activity. Nimustine alkylates and crosss DNA, thereby causing DNA fragmentation, inhibition of protein synthesis, and cell death.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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