l General Information |
Product Name | Estropipate |
General description | Estropipate is a form of estrogen, used to treat symptoms of menopause, also used to prevent osteoporosis. |
Synonym | 3-(Sulfooxy)-estra-1,3,5(10)-trien-17-one: piperazine (1:1), Estrone sulfate piperazine salt, Estropipate, Harmogen, Ogen |
Purity | ≥98.0%(HPLC) | CAS Number | 7280-37-7 |
Formula | C22H32N2O5S | Molecular Weight | 436.56488 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White to tan Solid |
Solubility(25°C) | DMSO | ≥50mg/ml |
l Biological Information |
Biochem/Physiol
Actions | Estropipate is a natural estrogenic substance composed of estrone sulfate and piperazine. Estropipate diffuses through the cell membrane and binds to and subsequently activates the nuclear estrogen receptor found in the reproductive tract, breast, pituitary, hypothalamus, liver, and bone. The activated complex binds to the estrogen response element on the DNA and activates the transcription of genes involved in the functioning of the female reproductive system and secondary sex characteristics. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
