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Raltegravir potassium

Product #: TS2485
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Details

l  General Information

Product Name

Raltegravir potassium

General description

Raltegravir Potassium is the orally bioavailable potassium salt of raltegravir, the first approved human immunodeficiency virus type 1 (HIV-1) integrase inhibitor.

Synonym

Raltegravir Potassium

Purity

≥97.0%(HPLC)

CAS Number

871038-72-1

Formula

C20H20FKN6O5

Molecular Weight

482.51

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Solid

Solubility(25°C)

DMSO

≥50mg/ml

Ethanol

≥5mg/ml

Water

Very slightly soluble

l  Biological Information

Biochem/Physiol  Actions

Raltegravir Potassium is the orally bioavailable potassium salt of a human immunodeficiency virus (HIV) integrase strand transfer inhibitor (HIV-1 INSTI) with HIV-1 antiviral activity. Raltegravir binds to and inhibits integrase, an HIV enzyme that inserts viral genetic material into the genetic material of the infected human cell. Inhibition of integrase prevents insertion of HIV DNA into the human DNA genome, thus blocking HIV replication.

Application

1.Anti-HIV Agents

2.HIV Integrase Inhibitors

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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