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4-Aminosalicylic acid

Product #: TS2457
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Details

l  General Information

Product Name

4-Aminosalicylic acid

General description

4-Aminosalicylic acid is an antitubercular agent with bacteriostatic activity against Mycobacterium tuberculosis.

Synonym

para-aminosalicylic acid, Aminosalicylic acid, 4-aminosalicylate, 4-amino-2-hydroxybenzoic acid

Purity

≥99.0%(HPLC)

CAS Number

65-49-6

Formula

C7H7NO3

Molecular  Weight

153.14

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to Pale Brown Solid

Solubility(25°C)

DMSO

≥5mg/ml

l  Biological Information

Biochem/Physiol  Actions

Aminosalicylic Acid is an analog of para-aminobenzoic acid (PABA) with antitubercular activity. Aminosalicylic acid exerts its bacteriostatic activity against Mycobacterium tuberculosis by competing with PABA for enzymes involved in folate synthesis, thereby suppressing growth and reproduction of M. tuberculosis, eventually leading to cell death.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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