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Diaveridine

Product #: TS2449
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l  General Information

Product Name

Diaveridine

General description

Diaveridine is coccidiostat with anti-parasitic activity and also a dihydrofolate reductase (DHFR) inhibitor preventing folic acid synthesis in species of Pneumocystis.

Synonym

AI3-23935, CCRIS-3784; 5-[(3,4-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine

Purity

≥98.0%(HPLC)

CAS Number

5355-16-8

Formula

C13H16N4O2

Molecular Weight

260.29

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to Yellow Solid

Solubility(25°C)

DMSO

≥15mg/ml

l  Biological Information

Biochem/Physiol  Actions

Diaveridine is an aminopyrimidine in which the pyrimidine  ring carries amino substituents at C-2 and C-4 and a 3,4-dimethoxybenzyl group at C-5. A folic acid antagonist, it is used as a synergist with sulfonamides against the parasitic Eimeria species. It has a role as an antiparasitic agent.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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