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alpha-Naphthoflavone

Product #: TS2433
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l  General Information

Product Name

alpha-Naphthoflavone

General description

Alpha-Naphthoflavone, a synthetic flavonoid, is a potent inhibitor of aromatase with an I50 value of 0.5 μM.

Synonym

7,8-benzoflavone; 2-phenylbenzo[h]chromen-4-one

Purity

≥98.0%(HPLC)

CAS Number

604-59-1

Formula

C19H12O2

Molecular Weight

272.30

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to off-white or Pale Yellow Solid

Solubility(25°C)

DMSO

≥25mg/ml

l  Biological Information

Biochem/Physiol  Actions

Alpha-naphthoflavone is an extended flavonoid resulting from the formal fusion of a benzene ring with the h side of flavone. A synthetic compound, it is an inhibitor of aromatase (EC 1.14.14.14). It has a role as an EC 1.14.14.14 (aromatase) inhibitor, an aryl hydrocarbon receptor antagonist and an aryl hydrocarbon receptor agonist. It is an organic heterotricyclic compound and an extended flavonoid.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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