l General Information |
Product Name | Sitagliptin |
General description | Sitagliptin is an oral and highly selective DPP-4 inhibitor with an IC50 of 18 nM. It is used for the treatment of type 2 diabetes. |
Synonym | MK-0431 |
Purity | ≥99.0%(HPLC) | CAS Number | 486460-32-6 |
Formula | C16H15F6N5O | Molecular Weight | 407.31 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25°C) | DMSO | ≥50mg/ml |
l Biological Information |
Biochem/Physiol
Actions | Sitagliptin is an orally available, competitive, beta-amino acid-derived inhibitor of dipeptidyl peptidase 4(DDP-4) with hypoglycemic activity. Sitagliptin may cause an increased risk in the development of pancreatitis. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
