l General Information |
Product Name | 4-Aminopyridine |
General description | 4-Aminopyridine (4-AP) is a potent and non-selective inhibitor of voltage gated potassium channels (Kv) with IC50 values of 170 μM and 230 μM for Kv1.1 and Kv1.2 in CHO cells, respectively. |
Synonym | fampridine, dalfampridine; pyridin-4-amine |
Purity | ≥98.0%(HPLC) | CAS Number | 504-24-5 |
Formula | C5H6N2 | Molecular Weight | 94.11 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White to off-white Solid |
Solubility(25°C) | DMSO | ~5mg/ml |
l Biological Information |
Biochem/Physiol
Actions | One of the POTASSIUM CHANNEL BLOCKERS with secondary effect on calcium currents which is used mainly as a research tool and to characterize channel subtypes. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
