l General Information |
Product Name | Tavaborole (AN-2690) |
General description | Tavaborole (AN-2690) is a boron-containing small molecule with broad spectrum antifungal activity. |
Synonym | Tavaborole; Kerydin; 5-fluoro-1-hydroxy-3H-2,1-benzoxaborole |
Purity | ≥98.0%(HPLC) | CAS Number | 174671-46-6 |
Formula | C7H6BFO2 | Molecular Weight | 151.93 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White to Beige Solid |
Solubility(25°C) | DMSO | ≥15mg/ml |
Ethanol | ≥15mg/ml |
Water | Very slightly soluble |
l Biological Information |
Biochem/Physiol
Actions | Tavaborole is a boron-containing small molecule antifungal agent with broad-spectrum activity against filamentous fungi, including both mold and yeast. 5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole inhibits fungal cytoplasmic leucyl-tRNA synthetase by preventing catalytic turnover, thus inhibiting synthesis of leucyl-tRNA(Leu) and consequentially blocking protein synthesis. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
