Product Name

Pyridoxal 5-phosphate monohydrate

General description

Pyridoxal 5-phosphate monohydrate is an active vitamin B6 metabolite, which is a cofactor in many reactions of amino acid metabolism.

Synonym

Pyridoxal phosphate hydrate; (4-formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate; hydrate

Purity

≥98.0%(HPLC)

CAS Number

41468-25-1

Formula

C⁸H¹²NO⁷P

Molecular Weight

265.16

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to Pale Brown Solid

Solubility(25°C)

DMSO

≥5mg/ml

l  Biological Information

Biochem/Physiol  Actions

Pyridoxal Phosphate is the active form of vitamin B6 and a coenzyme for many pyridoxal phosphate (PLP)-dependent enzymes. PLP is involved in numerous enzymatic transamination, decarboxylation and deamination reactions; it is necessary for the synthesis of amino acids and amino acid metabolites, and for the synthesis and/or catabolism of certain neurotransmitters, including the conversion of glutamate into gamma-aminobutyric acid (GABA) and levodopa into dopamine. PLP can be used as a dietary supplement in cases of vitamin B6 deficiency. Reduced levels of PLP in the brain can cause neurological dysfunction.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov