l General Information |
Product Name | Daminozide |
General description | Daminozide, a plant growth regulator, selectively inhibits the KDM2/7 JmjC subfamily with IC50 of 1.5±0.7 μM for KDM2A. It is at least 100-fold selective as an inhibitor of the KDM2/7 subfamily over the other demethylase subfamily members tested, with IC50s of 2 μM or less against KDM2A, PHF8, and KIAA1718 and IC50s of 127 μM for KDM3A or greater (mM range) against other demethylases. |
Synonym | Aminozide, Succinic Acid, 4-(2,2-dimethylhydrazinyl)-4-oxobutanoic acid |
Purity | ≥98.0%(GC) | CAS Number | 1596-84-5 |
Formula | C6H12N2O3 | Molecular Weight | 160.17 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White to Pale Yellow or Pale Brown Solid |
Solubility(25°C) | DMSO | ≥15mg/ml |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
