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Xanthurenic Acid

Product #: TS2154
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l  General Information

Product Name

Xanthurenic Acid

General description

Xanthurenic acid, a molecule arising from tryptophan metabolism by transamination of 3-hydroxykynurenine, activates mGlu2/3 Metabotropic glutamate receptors (mGlu2 and mGlu3).

Synonym

xanthurenate; 8-Hydroxykynurenic acid; 4,8-Dihydroxyquinaldic acid; 8-hydroxy-4-oxo-1H-quinoline-2-carboxylic acid

Purity

≥96.0%(HPLC)

CAS Number

59-00-7

Formula

C10H7NO4

Molecular Weight

205.17

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Solid

Solubility(25°C)

DMSO

Slightly soluble

l  Biological Information

Biochem/Physiol  Actions

Xanthurenic acid is a quinolinemonocarboxylic acid that is quinoline-2-carboxylic acid substituted by hydroxy groups at C-4 and C-8. It has a role as a metabotropic glutamate receptor agonist, an iron chelator, a vesicular glutamate transport inhibitor and an animal metabolite. It is a quinolinemonocarboxylic acid and a dihydroxyquinoline. It is a conjugate acid of a xanthurenate.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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