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β-thujaplicin

Product #: TS2151
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l  General Information

Product Name

β-thujaplicin

General description

β-Thujaplicin is a toxic tropolone derivative present in the heartwood of western red cedar (Thuja plicata) and is used as a preservative and antimicrobial additive in a number of commercial goods.

Synonym

Hinokitiol, β-TH, 4-Isopropyltropolone; 2-hydroxy-6-propan-2-ylcyclohepta-2,4,6-trien-1-one

Purity

≥99.0%(HPLC)

CAS Number

499-44-5

Formula

C10H12O2

Molecular Weight

164.2

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to Yellow Solid

Solubility(25°C)

DMSO

≥15mg/ml

l  Biological Information

Biochem/Physiol  Actions

Beta-thujaplicin is a monoterpenoid that is cyclohepta-2,4,6-trien-1-one substituted by a hydroxy group at position 2 and an isopropyl group at position 4. Isolated from Thuja plicata and Chamaecyparis obtusa, it exhibits antimicrobial activities. It has a role as an antifungal agent, an antibacterial agent, an antiplasmodial drug, an antineoplastic agent and a plant metabolite. It is an enol, a cyclic ketone and a monoterpenoid. It derives from a hydride of a cyclohepta-1,3,5-triene.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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