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4-Hydroxychalcone

Product #: TS2144
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Details

l  General Information

Product Name

4-Hydroxychalcone

General description

4-Hydroxychalcone is a chalcone metabolite with diverse biological activities. It inhibits TNFα-induced NF-κB pathway activation in a dose-dependent manner and also activates BMP signaling.

Synonym

P-Cinnamoylphenol; (E)-3-(4-hydroxyphenyl)-1-phenylprop-2-en-1-one

Purity

≥97.0%(HPLC)

CAS Number

20426-12-4

Formula

C15H12O2

Molecular Weight

224.25

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Solid

Solubility(25°C)

DMSO

≥25mg/ml

l  Biological Information

Biochem/Physiol  Actions

4-hydroxychalcone is a member of the class of chalcones that is trans-chalcone substituted by a hydroxy group at position 4. It has a role as a plant metabolite and an antihypertensive agent. It is a member of chalcones and a member of phenols. It derives from a trans-chalcone.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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