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Ondansetron Hydrochloride Dihydrate

Product #: TS2132
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Details

l  General Information

Product Name

Ondansetron Hydrochloride Dihydrate

General description

OndansetronHydrochloride is a highly specific and selective serotonin 5-HT3 receptor antagonist (Ki=6.16 nM), with low affinity for dopamine receptors.

Synonym

9-methyl-3-[(2-methylimidazol-1-yl)methyl]-2,3-dihydro-1H-carbazol-4-one; dihydrate; hydrochloride

Purity

≥98.0%(HPLC)

CAS Number

103639-04-9

Formula

C18H24ClN3O3

Molecular Weight

365.85

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to off-white Solid

Solubility(25°C)

DMSO

≥45mg/ml

Ethanol

≥25mg/ml

Water

≥45mg/ml

l  Biological Information

Biochem/Physiol  Actions

A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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