l General Information |
Product Name | Tamsulosin hydrochloride |
General description | Tamsulosin hydrochloride is a potent and selective α1a adrenergic receptor antagonist with Ki values of 0.13 nM, 1.92 nM and 0.18 nM for α1a-AR, α1b-AR and α1d-AR. |
Synonym | Tamsulosina hydrochloride, Tamsulosinum hydrochloride |
Purity | ≥99.0%(HPLC) | CAS Number | 106463-17-6 |
Formula | C20H29ClN2O5S | Molecular Weight | 444.97 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White to off-white Solid |
Solubility(25°C) | DMSO | ≥50mg/ml |
Water | ≥10mg/ml |
l Biological Information |
Biochem/Physiol
Actions | Tamsulosin Hydrochloride is the hydrochloride salt of tamsulosin, a sulfonamide derivative with adrenergic antagonist activity. Tamsulosin selectivity binds to and blocks the activity of alpha1 adrenoreceptors in the human prostate and bladder neck; blockade of these adrenoceptors can cause smooth muscle in the prostate and bladder neck to relax, resulting in an improvement in urinary flow rate. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
