l General Information |
Product Name | Guanfacine Hydrochloride |
General description | Guanfacine Hydrochloride is a selective α2A-adrenoceptor agonist with anti-hypertensive effect. |
Synonym | Guanfacine Hydrochloride, Guanfacine, Tenex, Intuniv |
Purity | ≥99.0%(HPLC) | CAS Number | 29110-48-3 |
Formula | C9H10Cl3N3O | Molecular Weight | 282.55 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White to off-white Solid |
Solubility(25°C) | DMSO | ≥35mg/ml |
Ethanol | ≥35mg/ml |
Water | ≥5mg/ml |
l Biological Information |
Biochem/Physiol
Actions | Guanfacine Hydrochloride is the hydrochloride salt form of guanfacine, a centrally acting alpha-2 adrenergic agonist with antihypertensive activity.
Alpha-2 receptor stimulation by guanfacine hydrochloride results in a decreased sympathetic outflow from the vasomotor center to the heart, kidneys, and peripheral vasculature. This leads to a decrease in heart rate and peripheral vascular resistance. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
