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Glycopyrrolate

Product #: TS2069
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Details

l  General Information

Product Name

Glycopyrrolate

General description

Glycopyrrolate is a muscarinic antagonist used as an antispasmodic, in some disorders of the gastrointestinal tract, and to reduce salivation with some anesthetics.

Synonym

Glycopyrrolate bromide, Glycopyrronium bromide, Robinul, Gastrodyn

Purity

≥98.0%(HPLC)

CAS Number

596-51-0

Formula

C19H28BrNO3

Molecular Weight

398.33

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to tan Solid

Solubility(25°C)

DMSO

≥45mg/ml

Ethanol

≥35mg/ml

Water

≥45mg/ml

l  Biological Information

Biochem/Physiol  Actions

Glycopyrrolate is a synthetic quaternary ammonium that is an anticholinergic agent with antispasmodic activity. Glycopyrrolate competitively binds to peripheral muscarinic receptors in the autonomic effector cells of, and inhibits cholinergic transmission in smooth muscle, cardiac muscle, the sinoatrial (SA) node, the atrioventricular (AV) node, exocrine glands and in the autonomic ganglia. Blockage of cholinergic transmission, in smooth muscle cells located in the gastrointestinal tract and the bladder, causes smooth muscle relaxation and prevents the occurrence of painful spasms. In addition, glycopyrrolate inhibits the release of gastric, pharyngeal, tracheal, and bronchial secretions.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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