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Hexachlorophene

Product #: TS2047
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Details

l  General Information

Product Name

Hexachlorophene

General description

Hexachlorophene is a potent KCNQ1/KCNE1 potassium channel activator with EC50 of 4.61 ± 1.29 μM It can also attenuate Wnt/beta-catenin signaling through the Siah-1-mediated beta-catenin degradation.

Synonym

Hexachlorofen, Fostril, Nabac, pHisoHex, 3,4,6-trichloro-2-[(2,3,5-trichloro-6-hydroxyphenyl)methyl]phenol

Purity

≥99.0%(HPLC)

CAS Number

70-30-4

Formula

C13H6Cl6O2

Molecular Weight

406.9

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Solid

Solubility(25°C)

DMSO

≥45mg/ml

Ethanol

≥45mg/ml

Water

Very slightly soluble

l  Biological Information

Biochem/Physiol  Actions

Hexachlorophene is a chlorinated bisphenol antiseptic agent with bacteriostatic activity. Hexachlorophene is used topically in soaps, creams and dermatological preparations and is active against gram-positive organisms, but much less effective against gram-negative organisms.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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