l General Information |
Product Name | Dithranol |
General description | Dithranol is one of the most important local therapeutic agents against the common skin disease, psoriasis. |
Synonym | Anthralin; cignoline; 1,8,9-trihydroxyanthracene; 1,8-dihydroxy-10H-anthracen-9-one |
Purity | ≥97.0%(HPLC) | CAS Number | 1143-38-0 |
Formula | C14H10O3 | Molecular Weight | 226.23 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25°C) | DMSO | Slightly soluble |
l Biological Information |
Biochem/Physiol
Actions | Anthralin is a natural anthraquinone derivative, anti-psoriatic and anti-inflammatory Anthralin (dithranol) controls skin growth by reducing DNA synthesis and mitotic activity in the hyperplastic epidermis, restoring a normal rate of cell proliferation and keratinization. Used topically in the treatment of psoriasis, dermatoses, and alopecia areata, it is also used in biomedical research due to its effect on EGFR autophosphorylation. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
