Product Name

Eflornithine hydrochloride hydrate

General description

Eflornithine hydrochloride inhibits polyamine biosynthesis by the selective, irreversible inhibition of ornithine decarboxylase (ODC). A chemoprotective agent that blocks angiogenesis. Its biological half-life is 8 hours.

Synonym

Difluoromethylornithine hydrochloride hydrate; 2,5-diamino-2-(difluoromethyl)pentanoic acid; hydrate; hydrochloride

Purity

≥98.0%(T)

CAS Number

96020-91-6

Formula

C⁶H¹⁵ClF²N²O³

Molecular Weight

236.64

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to Off White Solid

Solubility(25°C)

DMSO

Very slightly soluble

Ethanol

Very slightly soluble

Water

≥40mg/ml

l  Biological Information

Biochem/Physiol  Actions

An inhibitor of ornithine decarboxylase, the rate limiting enzyme of the polyamine biosynthetic pathway.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov