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Nitrofurantoin

Product #: TS1981
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Details

l  General Information

Product Name

Nitrofurantoin

General description

Nitrofurantoin is an antibiotic used to treat bladder infections.It inhibits bacterial DNA, RNA, and cell wall protein synthesis.

Synonym

Macrodantin, Furadantine, Furadonine; 1-[(E)-(5-nitrofuran-2-yl)methylideneamino]imidazolidine-2,4-dione

Purity

≥98.0%(HPLC)

CAS Number

67-20-9

Formula

C8H6N4O5

Molecular Weight

238.159

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Yellow Solid

Solubility(25°C)

DMSO

≥35mg/ml

Water

Very slightly soluble

l  Biological Information

Biochem/Physiol  Actions

Nitrofurantoin is a synthetic derivative of imidazolidinedione, Nitrofurantoin inhibits bacterial DNA, RNA, and cell wall protein synthesis. Activated by bacterial flavoproteins to intermediates that inactivate bacterial ribosomal proteins, Nitrofurantoin is used prophylactically as a urinary anti-infective agent against most gram-positive and gram-negative organisms and for long-term suppression of infections.

Application

1.Anti-Bacterial Agents

2.Anti-Infective Agents, Urinary

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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