l General Information |
Product Name | Mefloquine HCl |
General description | Mefloquine HCl is a blood schizonticide by inhibiting hemozoin formation, used as an antimalarial drug. |
Synonym | (S)-[2,8-bis(trifluoromethyl)quinolin-4-yl]-[(2R)-piperidin-2-yl]methanol; hydrochloride |
Purity | ≥98.0%(HPLC) | CAS Number | 51773-92-3 |
Formula | C17H17ClF6N2O | Molecular Weight | 414.776 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White to off-white Solid |
Solubility(25°C) | DMSO | ≥50mg/ml |
Water | Very slightly soluble |
l Biological Information |
Biochem/Physiol
Actions | Mefloquine Hydrochloride is the hydrochloride salt form of mefloquine, a piperidinyl quinidine with antimalarial activity. Although the exact mechanism of mefloquine hydrochloride is largely unknown, this agent acts as a blood schizonticide and probably exert its actions by interacting with the phospholipid b, thereby interfering with the stability of the cell membrane and causing cell lysis. Mefloquine hydrochloride is active against Plasmodium falciparum and Plasmodium vivax. |
Application | Antimalarials |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
