l General Information |
Product Name | Nalmefene HCl |
General description | Nalmefene is an opioid receptor antagonist, it is used primarily in the management of alcohol dependence. |
Synonym | (4R,4aS,7aS,12bS)-3-(cyclopropylmethyl)-7-methylidene-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol; hydrochloride |
Purity | ≥98.0%(HPLC) | CAS Number | 58895-64-0 |
Formula | C21H26ClNO3 | Molecular Weight | 375.893 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25°C) | DMSO | ≥50mg/ml |
Water | ≥50mg/ml |
l Biological Information |
Biochem/Physiol
Actions | Nalmefene Hydrochloride is the hydrochloride salt form of nalmefene, a naltrexone analogue with opioid antagonistic property. Nalmefene antagonizes the effects of opioids by competing for the opioid receptors in the CNS. This results in reversal of the effects of the opioids, including reversal of analgesia, euphoria, respiratory depression, hypotension, sedation and physical dependence. |
Application | Narcotic Antagonists |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
