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Mupirocin

Product #: TS1891
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Details

l  General Information

Product Name

Mupirocin

General description

Mupirocin is an isoleucyl t-RNA synthetase inhibitor, used in the treatment of bacterial skin infections. 

Synonym

9-[(E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[[(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl]methyl]oxan-2-yl]-3-methylbut-2-enoyl]oxynonanoic acid

Purity

≥97.0%(HPLC)

CAS Number

12650-69-0

Formula

C26H44O9

Molecular Weight

500.629

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to tan Solid

Solubility(25°C)

DMSO

≥50mg/ml

Water

≥35mg/ml

l  Biological Information

Biochem/Physiol  Actions

Mupirocin is a natural crotonic acid derivative extracted from Pseudomonas fluorescens. Mupirocin inhibits bacterial protein synthesis by specific reversible binding to bacterial isoleucyl tRNA synthase. With excellent activity against gram-positive staphylococci and streptococci, it is primarily used for treatment of primary and secondary skin disorders, nasal infections, and wound healing.

Application

1.Anti-Bacterial Agents

2.Protein Synthesis Inhibitors

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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