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Benzocaine

Product #: TS1831
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Details

l  General Information

Product Name

Benzocaine

General description

Benzocaine is the ethyl ester of p-aminobenzoic acid (PABA), it is a local anesthetic commonly used as a topical pain reliever or in cough drops.

Synonym

ethyl 4-aminobenzoate

Purity

≥99.0%(HPLC)

CAS Number

94-09-7

Formula

C9H11NO2

Molecular Weight

165.192

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to off-white Solid

Solubility(25°C)

DMSO

≥25mg/ml

Ethanol

≥25mg/ml

Water

Very slightly soluble

l  Biological Information

Biochem/Physiol  Actions

Benzocaine is an ester of paraaminobenzoic acid, lacking the terminal diethylamino group of procaine, with anesthetic activity. Benzocaine binds to the sodium channel and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions. Depolarization of the neuronal membrane is inhibited, thereby blocking the initiation and conduction of nerve impulses.

Application

Anesthetics, Local

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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