Product Name

Mezlocillin Sodium

General description

Mezlocillin sodium is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms.

Synonym

sodium; (2S,5R,6R)-3,3-dimethyl-6-[[(2R)-2-[(3-methylsulfonyl-2-oxoimidazolidine-1-carbonyl)amino]-2-phenylacetyl]amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

Purity

≥99.0%(HPLC)

CAS Number

42057-22-7

Formula

C²¹H²⁴N⁵NaO⁸S²

Molecular Weight

561.56

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to off-white Solid

Solubility(25°C)

DMSO

≥50mg/ml

Ethanol

Insoluble

Water

≥50mg/ml

l  Biological Information

Biochem/Physiol  Actions

Mezlocillin Sodium Monohydrate is the monohydrate and sodium salt form of mezlocillin, a broad-spectrum, semisynthetic ampicillin-derived acylureidopenicillin with antibacterial activity. Mezlocillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-age of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov