l General Information |
Product Name | Desvenlafaxine |
General description | Desvenlafaxine is a serotonin (5-HT) and norepinephrine (NE) reuptake inhibitor with Ki of 40.2 nM and 558.4 nM, respectively. |
Synonym | WY 45233; 4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol |
Purity | ≥99.0%(HPLC) | CAS Number | 93413-62-8 |
Formula | C16H25NO2 | Molecular Weight | 263.381 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25°C) | DMSO | ≥25mg/ml |
Ethanol | Slightly soluble |
Water | Very slightly soluble |
l Biological Information |
Biochem/Physiol
Actions | Desvenlafaxine is a synthetic phenethylamine bicyclic derivative with antidepressant activity. Desvenlafaxine is a selective reuptake inhibitor of serotonin and norepinephrine due to its high binding affinities to the pre-synaptic serotonin and norepinephrine transporters. By blocking both transporters, this agent prolongs neurotransmitter activities of both serotonin and norepinephrine, thereby alleviating depressive state. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
