l General Information |
Product Name | Sodium 4-Aminosalicylate |
General description | Sodium 4-Aminosalicylate is an antibiotic used to treat tuberculosis via NF-κB inhibition and free radical scavenging. |
Synonym | sodium; 4-amino-2-hydroxybenzoate; dihydrate |
Purity | ≥99.0%(HPLC) | CAS Number | 6018-19-5 |
Formula | C7H6NNaO3 | Molecular Weight | 211.149 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25°C) | DMSO | ≥25mg/ml |
Ethanol | Insoluble |
Water | ≥25mg/ml |
l Biological Information |
Biochem/Physiol
Actions | Aminosalicylate Sodium is the sodium salt form of aminosalicylic acid, an analog of para-aminobenzoic acid (PABA) with antitubercular activity. Aminosalicylate sodium exerts its bacteriostatic activity against Mycobacterium tuberculosis by competing with PABA for enzymes involved in folate synthesis, thereby suppressing growth and reproduction of M. tuberculosis, eventually leading to cell death. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
