l General Information |
Product Name | Hexamethonium Dibromide |
General description | Hexamethonium Dibromide is a selective antagonist of neuronal-type nicotinic AChR in ganglia. |
Synonym | trimethyl-[6-(trimethylazaniumyl)hexyl]azanium; dibromide |
Purity | ≥99.0%(HPLC) | CAS Number | 55-97-0 |
Formula | C12H30Br2N2 | Molecular Weight | 362.194 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25°C) | DMSO | Insoluble |
Ethanol | Insoluble |
Water | ≥45mg/ml |
l Biological Information |
Biochem/Physiol
Actions | A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
